NAIA Official Blog

An exciting new program was unveiled two weeks ago at the Rose City Classic dog show in Portland, Oregon: the testing and grading of respiratory function in brachycephalic dogs. This was launched by the Orthopedic Foundation for Animals (OFA), in conjunction with the Bulldog, French Bull Dog, and Pug Dog Clubs of America, as well as the AKC itself.

If you are subscribed to this blog, you probably already know what a brachycephalic breed of dog is and the health concerns and controversies that swirl around them. What you may not know – what too many people, frankly, don’t know – is that reputable breeders and their breed clubs have been hard at work to address and breed away from health issues associated with shortened snouts when present, and to, ahem, clear the air regarding some of the exaggerations surrounding brachycephalic breeds. This test, the Respiratory Function Grading Scheme (RFGS), provides the public and prospective dog owners with objective proof of that work, and ideally, opens the door for constructive conversations on health testing and issues with purpose-bred animals.

For dogs and their breeders, the RFGS objectively measures and grades brachycephalic obstructive airway syndrome (BOAS) using a dog’s rest state and its breathing after exercise. This gives breeders valuable information on their dog’s overall health, provides guidelines for which dogs they should breed, and as a bonus, serves as a reference that sets themselves and their breeding programs apart. While it is true many top breeders were already focused on this issue, this tool offers them the opportunity, through a veterinary assessment, to certify that their dogs have normal respiratory function.

Over time, this can’t help but contribute to the advancement of good health in well-bred brachycephalic dogs both in reality as well as in public consciousness, which would be fantastic. To quote Eddie Dziuk, OFA’s chief operating officer, “There’s no reason a Pug shouldn’t be able to run around and breathe easily.” A majority already can, and with programs like this and smart choices by breeders, even more will be!

Resources
★     Respiratory Function Grading Scheme
★     PHOTOS: See the fabulous floofs of the Rose City Classic Dog Show

With inflation being such a major news item all throughout 2022, the recent spike in egg and poultry prices may have slid under your radar as part of the general increased cost of living. However, if you break it down, a dozen large, grade A eggs cost 60% more than they did a year ago – more than seven times higher than last year’s rate of inflation! – and this increased cost is due to something far more dire than disruptions to the supply chain: it’s avian influenza. It is back in a big way, in an outbreak the USDA is calling the largest animal emergency they have ever faced in this country.

We are all probably aware of avian influenza, at least to the extent that it exists and makes birds sick. But there’s a lot more to it than that. There are several strains of the virus, and more importantly, it is split into two groups: low pathogenic avian influenza (LPAI) and highly pathogenic avian influenza (HPAI). LPAI, as you may have already guessed, is not as lethal and has a wide range of outcomes: infected birds may suffer from zero clinical signs of the virus, they may sicken enough to die from it, or fall somewhere in between on the spectrum. Despite the fact many birds recover from it, it is still a problem as well as worrisome, since two of the strains are known to mutate into highly pathogenic forms. HPAI, the group threatening farmer’s flocks right now, spreads more rapidly and is far more deadly – especially to domestic poultry.

Since last February, more than 58 million birds have been culled due to the virus, 40 million of them egg-laying chickens. These numbers are despite improvements in monitoring and biosecurity protocols since the last major outbreak in 2015. And unfortunately, preventing and limiting outbreaks could become even more difficult as time progresses, since HPAI appears more and more prevalent in wild birds. Unlike chickens, numerous wild birds carry HPAI without showing serious signs of illness… and they migrate all throughout the world.

Commercial and backyard farmers, the USDA, researchers, and others are all working to find ways of protecting the animals we care for from this terrible illness, but it has been a painfully difficult path, and sadly, there is no obvious quick fix on the horizon.

Resources
★     USGS: What are the different types of avian influenza?
★     Grizzly bears test positive for bird flu in Montana, officials say

Saying “The Devil made me do it” is a well-known and lighthearted – but ultimately meaningless – way of exploiting theology to avoid accountability for our actions. But saying “The protozoans made me do it,” even if it doesn’t roll off the tongue quite so easily, actually has some scientific backing. There is a growing body of evidence that parasites play a large role in influencing animal behaviors… and one of the best known, Toxoplasma gondii, lives in the bellies of North America’s second-most beloved pet: the common housecat.

Many animal lovers already know about the effect of toxoplasmosis on rodents. In a nutshell, cats are the only host T. gondii can reproduce inside of… and wouldn’t you know it: toxoplasmosis-infected rats don’t show the same aversion to cat urine, making these rodents (and the parasites they are carrying) more likely to find their way into a cat’s stomach. This is a convenient coincidence (except for the rat)!

But such convenient coincidences may be just the tip of the iceberg. Newer research in the wild shows T. gondii-infected chimps and hyena cubs attracted to the urine of large, predatory cats. And infected humans display differences in behavior, too. While the odds of us being eaten by a cat are quite small, people suffering from toxoplasmosis engage in notably more risk-taking behaviors, and demonstrate less fear of failure when compared to the general population. Past experiences, our environment, genes, and social expectations are well-known factors that shape behavior, but as we’re learning with parasites like T. gondii, there may be numerous lesser-known – but significant – factors at play, as well!

Resources
★     Brain parasite may strip away rodents’ fear of predators—not just of cats
★     Toxoplasmosis in Cats

For such an anodyne-sounding term, the word “bycatch” can be quite the grenade. It is generally associated with commercial fishing, and, at its most basic level, refers to any species of animal you didn’t intend to catch while fishing. Crabs, the wrong species of fish, and – perhaps most famously – dolphins all come to mind as examples of bycatch. However, while the term is accurate, albeit vague, “bycatch” is also viewed as an enraging, industry-manufactured euphemism by animal rights activists and some of the more vociferous critics of commercial fishing. To them, it is a term that “sugarcoats the indefensible” – waste, suffering, ecological devastation (you know the drill). OK, that’s predictably over-the-top, but we’ll concede that bycatch sits among industry buzzwords like “harvest” or “free-range,” that, even when well-intentioned, have the potential to raise at least as many questions as they answer.

Subtlies of language aside, bycatch is indeed a serious problem (ask the world’s 10 surviving vaquitas their opinion on this issue). However, it must be acknowledged there have been many recent techniques and tools devised to reduce bycatch, several of which have already been implemented. Some of them are already enjoying dramatic success.

Off the coast of Alaska, where pollock are caught (pollock are the white groundfish that often end up in fish fillet sandwiches), there is a long history of salmon bycatch. This is bad news, as there are indigenous people who depend on salmon for food, and some of the Pacific salmon species are endangered. However, the nets used by Alaskan pollock fishers now use salmon excluders, which allow salmon to escape from pollock nets.

A more colorful solution comes from Oregon, where it was recently discovered that an ecologically vital smelt, the eulachon, will follow LED lights (especially green ones) placed on the bottom of a shrimp net, keeping them from being inadvertently scooped up. Interestingly, nobody is quite sure why eulachons follow the lights – but follow they do, and that is the important thing.

For seabirds, the oft-forgotten victims of bycatch, streamers (called tori lines or, more aptly, bird-scaring lines) have been equipped on many boats, flapping threateningly over fishing lines, and more importantly, over the tantalizing bait that birds sometimes attack and get hooked on. When used properly, these lines have been hugely successful.

And finally, for our beloved cetaceans, instead of visual cues, a device called a banana pinger (surprise! – it looks much like a mechanical banana) is now being attached to fishing nets, emitting obnoxious high-frequency pings when submerged. The good news so far: dolphins and porpoises are not fans of it! There has been some fear that hungry porpoises, clever as they are, would become habituated to the noise, and begin exploring the delicious interiors of fishing nets once again, but so far, there is little evidence of that happening.

While none of these innovations are perfect, they make a difference and are chasing an important ideal… and more are finding their way into the field (and the water) every day.

Resources
★     Streamer (tori) lines
★     A sound idea: ‘Banana Pinger’ audio device could help reduce porpoise bycatch
★     ‘Cocaine of the sea’ threatens critically endangered vaquita

Ask the average Jane or Joe about dog breeding, and their most distant point of reference probably goes back 17 years to the mockumentary film Best in Show. If they have a friend or relative who breeds dogs, add another 20 years on to that total. And if they’re history buffs, they might be able to go back to the late Victorian era.

But people have been purposefully breeding dogs for a lot longer than that. Thousands of years, in fact — and new findings are pointing all the way back to the hunter-gatherers of Zhokhov Island 9,000 years ago…

Now it appears these ancient Arctic dwellers did something even more remarkable: They may have been among the first humans to breed dogs for a particular purpose. An analysis of canine bones from Zhokhov suggests the dogs there were bred to pull sleds, making this the first evidence—by thousands of years—for dog breeding in the archaeological record.

As these findings indicate, the length and depth of the human-dog bond is truly astounding.

This fascinating and inspiring read from Tufts was shared with us yesterday: Curiosity Saved the Cats.

From the perspectives of science, animal welfare, and human health alone it is very much worth reading. Animal science is an invaluable discipline that improves and saves countless human and animal lives, as illustrated clearly here. But there are several other facets to this story we found interesting as well, and it is worth approaching this article with those in mind:

• Scientists and pet owners working together. This is stated plainly in the article itself, but think for a moment about the level of trust and cooperation required to carry out the research. How impressive is that? It also raises an important question: do we still have that level of trust today, and if not, what can we do to regain it?
• It is hard not to cringe when you read about a house with more than 100 cats, regardless of the condition the cats are being kept in. Yet, these crowded conditions are what led to the isolation and treatment of HIV in humans. This is the kind of historical tidbit that really forces you to hold more than one thought in your head at a time.
• The hostility faced by these scientists, who were approaching this issue with a then-controversial belief that viruses could cause cancer, is astounding. Ridicule, denial, rejection. It really speaks to the human condition: beware challenging established and comforting beliefs. Thank goodness these scientists were not deterred. It is simply amazing what just a few years can do for our understanding of disease and treatments.
• And speaking of pushing on bravely: note how they were not sure at the time whether FeLV was transmissible to humans or not (today, people are more concerned about Toxoplasma gondii); it’s no big deal today, but it took some guts to do their research. It can be frustrating seeing lazy portrayals of scientists in popular media, especially scientists who work with animals. Finding examples of socially awkward, aloof or perhaps even sadistic scientists on your television screen is easy (and this is completely ignoring the “mad scientist” archetype), while right here in real life, we have scientists like these who are passionate about finding answers that save lives!
• Finally, tying up both our “cooperation” and “understanding” threads — the huge contribution of veterinarians and animal shelters who joined the battle against FeLV, changing protocols, testing and vaccinating, ultimately saving the lives of millions of cats. These are the kind of things we can accomplish when we all work together.

Run For Research Awareness!

Registration is now OPEN to anyone, anywhere! Visit the link below to sign-up for the Homes for Animal Heroes Virtual 5K and become a Fundraiser as a Team Captain, join an existing team, or make a donation!

Homes for Animal Heroes Virtual 5k

Virtually every treatment, cure, vaccine, diagnostic and surgical procedure available today has been made possible through research involving animals. If you have ever taken cold or allergy medicine, used an asthma inhaler, had an x-ray, been treated for cancer, received insulin, taken antibiotics (just to name a few), YOU have directly benefited from research involving animals.

Homes for Animal Heroes (HAH) is a national network that works with the research community to rehome former research dogs into their forever homes, and share the TRUTH about biomedical research! We need your support in order to expand the HAH network and rehome animal heroes in every US state!

Click here to JOIN the RACE to Rehome Animal Heroes & Raise Awareness for Research!

Also: don’t forget to visit the Homes for Animal Heroes website and to like the Homes for Animal Heroes Facebook page!

Thanks to the recent study published by Pediatric Oncologist, Dr. Joshua Schiffman and his colleagues, the elephant’s resistance to cancer, and how it may be applied to humans has been in the news a lot recently:

Of the nearly 650 elephants analyzed, Schiffman’s team found that only about 5% died from cancer. That’s an incredible statistic, considering the cancer mortality rate in humans ranges from 11% to 25%.

This is some fascinating stuff, and what you might not know is the role the Ringling Bros. Center for Elephant Conservation (CET) is playing in this exciting research. Check this out:

Instrumental to this research is elephant DNA, and Dr. Schiffman needed a diverse gene pool to effectively study to species. Because the CEC has the largest herd of Asian elephants in the Western Hemisphere, the Feld Family felt compelled to help support this research. The incredible bond the staff has with these majestic animals, and the hands-on care provided at the Center for Elephant Conservation, allows the experts at the CEC to easily provide the blood samples Dr. Schiffman needs to further his research.

Dr. Dennis Schmitt, Ringling Bros. and Barnum & Bailey® Chair of Veterinary Services and Director of Research, and Dr. Wendy Kiso, Ringling Bros. Center for Elephant Conservation Research and Conservation Scientist, and other scientific collaborators on their team, have identified a key genetic link, called P53, that helps to protect both Asian and African elephants from developing cancer. The P53 gene’s job is to make sure that none of the cells in the body develop cancer. By studying the DNA in blood from elephants and the DNA in blood from patients with cancer, the team discovered that elephants have 40 copies of this P53 gene that attacks cancer while a healthy person has two copies.

Very cool findings! As humans work to preserve these majestic animals, will they in turn provide us with important keys in the battle against cancer? That would be certainly be poetic.

Oh — and by the way, Dr. Wendy Kiso will be presenting on the challenges and opportunities in saving the Asian Elephant at this year’s NAIA conference, in case you haven’t signed up already!

If you’ve ever wondered why cat’s eyes look so cool, check out this explanation that covers both predator and prey:

We found animals with vertically elongated pupils are very likely to be ambush predators which hide until they strike their prey from relatively close distance. They also tend to have eyes on the front of their heads. […]

In contrast, horizontally elongated pupils are nearly always found in grazing animals, which have eyes on the sides of their head. They are also very likely to be prey animals such as sheep and goats.

Why is this? Essentially, modeling shows that vertically elongated pupils allow a predator the ability to judge distances without moving its head, thus giving prey fewer opportunities to notice its approach. At the same time, prey with elongated horizontal pupils and eyes on the sides of their head are able to see nearly the entire area around their bodies, providing them with a keen early warning system against predators.

Pretty neat stuff — definitely worth reading about!

Measures and Countermeasures

Arnold L. Goldman DVM, MPH

“Gonadectomy in Dogs,” in other words, the sterilization of dogs by removal of testes or ovaries was the subject of a recent roundtable webinar created collaboratively by a Florida multi-specialty veterinary hospital, Coral Gables Animal Hospital, the American Veterinary Medical Association (AVMA) and the American Animal Hospital Association (AAHA). It can be viewed here.

The creation and intent of the webinar is to acknowledge that recent research shows that the sterilization procedures discussed are “not as innocuous” as previously believed to be, that today we recognize sterilization “reduces the risk of some cancers and medical conditions, but increases the risk of others” and that veterinarian’s thinking on this subject is “evolving.” The description of the program states: “Honest and transparent conversations must take place within the profession as well as between veterinarians and pet owners.”

In the webinar several veterinary specialists and a generalist discuss and debate some of the new information on sterilization and the new questions raised relative to what veterinarians have long advocated, sterilization for most.

The discussion centers primarily on the medical aspects of sterilization surgery, and what is most notable is just how uncertain the doctors are that the long held dogma of “sterilize everything and early” is still the right thing to tell their clients. I interpret what they say and also what they do not say as indicating that the point-of-view of these veterinarians has shifted to one of a more open-minded, wait-and-see point of view regarding elective sterilization surgery. You can almost hear some of them struggling to avoid undermining what they may still believe will be vindicated in the long term, that sterilization is good for individual animals.

If it turns out that sterilization is not in the medical interests of most individual veterinary patients after all however, no veterinarian wants to be in a position of continuing to advocate for something that harms their patients. And that is the key point: that veterinarians in individual animal practice are first obligated to their own clients and patients, and only then to any broader societal goals. We must always place our individual patients first.

That point-of-view may pose an internal ideological conflict for a shelter-employed veterinarian, who may see their individual patients, pre-adoption, mainly as elements of a larger societal enterprise, one dedicated to reducing un-owned or unwanted animals, unintended reproduction, euthanasia of healthy animals and all the forms of human irresponsibility that leads to these things.

Still, once an animal is owned and that animal is brought to a veterinarian, regardless of the animal’s origins, for that veterinarian, that owner and that patient, the patient’s interests must come ahead of any broader goals of the organization or facility from which the animal came. That is what our Oath instructs and what the public expects of us.

Veterinarian’s Oath
Being admitted to the profession of veterinary medicine, I solemnly swear to use my scientific knowledge and skills for the benefit of society through the protection of animal health and welfare, the prevention and relief of animal suffering, the conservation of animal resources, the promotion of public health, and the advancement of medical knowledge.
I will practice my profession conscientiously, with dignity, and in keeping with the principles of veterinary medical ethics.
I accept as a lifelong obligation the continual improvement of my professional knowledge and competence.